Q & A

Stasis (Venous) Ulcers, Diabetic Foot Ulcers (DFU), Pressure Ulcers (Bed Sores), Post Surgical Ulcers,
1st and 2nd degree burns, cuts, abrasions and minor skin irritations.

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The unique combination of SilverStream’s ingredients kills bacteria, reduces bio-burden and destroys biofilms. Its non-toxic, non-cytotoxic properties stimulate growth of granulation tissue. SilverStream prevents maceration and facilitates the absorption and reduction of exudates, while keeping the wound moist for longer periods (due to the Hydrogel property) thus accelerating the wound healing process.

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The Tween 20 surfactant/detergent, together with menthol, destroys the biofilm protective layer and enables the penetration of silver ions into the bacteria cells, which then kills them.

 

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During the development of SilverStream, we discovered  that there is a synergic effect between the silver ions and menthol, which enhances the penetration of silver ions through the bacteria cell wall into the bacteria. This enabled us to ensure  that the concentration of silver ions remains  below the toxic and cytotoxic levels.

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The presence of a high concentration of hygroscopic glycerol gives SilverStream its hydrogel properties due to the reduction of water activity by the glycerol, preventing the growth of micro-organisms. These hydrogel properties also help SilverStream to keep the wound moist for a longer time.

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Silver particles do not penetrate efficiently into the bacteria cells, while silver ions - when penetrating the bacteria cells -  react and destroy the DNA and protein  functions.  

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SilverStream promotes granulation tissue growth, prevents maceration, relieves pain and helps eliminate bad odor. 

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As long as the daily use is restricted to 120mL or less,  treatment may be continued without any  time limitation.

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The age or the condition of the wound  does not limit  the use of SilverStream treatment for the approved indications. Our clinical experience illustrates that stagnant and tenacious wounds have been successfully treated with SilverStream until complete healing was achieved.

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No. In fact most patients found the effect of SilverStream soothing. The patient may initially feel a stinging sensation – but that will dissipate in a short time followed by a slight cooling sensation (due to the presence of menthol) that contributes to the overall soothing effect. 

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No. Due to the lower concentration of active Silver Ions, no damage is caused to the surrounding normal skin. Also, no pigmentation or darkening of the skin has been observed.

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No. The SilverStream solution is applied directly onto the wound while the syringe is kept ~1-2 cm away.

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SilverStream should be used by itself as a stand-alone solution. The wound can be washed with water or soapy water  prior to the application. The use of any other solutions in combination with SilverStream might reduce its efficacy.

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The hypertonic property of the solution prevents maceration and facilitates the mechanical removal of exudates and micro-organisms.

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Debridement in any form is symbiotic to use of SilverStream and hence, surgical removal/ debridement of necrotic tissue is beneficial as co-therapy with SilverStream.

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During both  case studies and clinical use worldwide, the elimination of infection and wound healing are evaluated by the wound color, odor, texture, tissue redness, formation of granulation tissues etc. Lab tests performed on typical clinical pathogens including MRSA and P. aeruginosa showed broad anti-microbial efficacy of SilverStream.

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59% wound size reduction in wounds measuring  between 1-15 cm2  , within just  4 weeks  (a superior result in comparison with  Sheehan Criteria)

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As many as needed during the course of treatment, within 28 days after the first puncture.

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Yes. SilverStream can be used effectively as the irrigant for either continuous or intermittent NPWT.

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Glycerol and menthol contribute to the pain relief effect of SilverStream, as well as accelerated Wound Healing induced by the solution.

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